ANTICORPS ANTI-INTEGRINE ALPHA-2 ET LEURS UTILISATIONS

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专利权人:

GLENMARK PHARMACEUTICALS S.A.

发明人:

申请号：

EP06804739.8

公开号：

EP1948798B1

申请日:

2006.11.17

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The invention relates to anti-±2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of ±2 integrin and inhibit the interaction of ±2²1 integrin with collagen. Also disclosed are therapeutic uses of anti-±2 integrin antibodies in treating ±2²1-mediated disorders, including anti-±2 integrin antibodies that bind to ±2 integrin without activating platelets.

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