592765 Disclosed is a pharmaceutical composition for controlled delivery of at least one active ingredient (3) into an aqueous phase. The composition comprises a tablet with at least one active ingredient (3) and optionally excipients and a coating (2), applied on the tablet, the coating (2) covering at least part of the tablet to impede the release of the at least one active ingredient (3) from at least part of the surface of the tablet. The coating (2) is applied in a manner allowing the release of the at least one active ingredient (3) from the tablet after contacting the pharmaceutical composition with the aqueous phase, establishing one or more degradation surfaces of the tablet. The coating is diminished in thickness or not present over a sharp edge or the composition (6). The first derivative of the area of each degradation surface with respect to time is larger than or equal to zero.
