Complexes of lumacaftor and its salts and derivatives, process for the preparation thereof and pharmaceutical compositions containing them

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专利权人:

Druggability Technologies IP Holdco Limited

发明人:

Karpati Richard Balazs,Szabone Ordasi Betti,Basa-Denes Orsolya,Angi Erzsebet Reka,Jordan Tamas,dr. Molnar Laszlo,dr. Glavinas Hristos,dr. Oetvoes Zsolt,dr. Filipcsei Genoveva

申请号：

HU1600269

公开号：

HU1600269A2

申请日:

2016.04.25

申请国别(地区):

HU

年份:

2017

代理人:

摘要：

The present invention relates to pharmaceutically acceptable complex formulation comprising complexes of Lumacaftor, or a salt, or derivatives thereof and complexation agents and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulations of the present invention have improved dissolution and permeability in fasted and fed state simulation that is expected to deliver full absorption and the elimination of the food effect.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/