Szabóné Ordasi, Betti,Basa-Dénes, Orsolya,Angi, Erzsébet Réka,Jordán, Tamás,Molnár, László,Glavinas, Hristos,Ötvös, Zsolt,Filipcsei, Genovéva,Kárpáti, Richard Balázs
申请号：
AU2017256182
公开号：
AU2017256182A1
申请日:
2017.04.25
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates to pharmaceutically acceptable complex formulation comprising complexes of Lumacaftor, or a salt, or derivatives thereof and complexation agents and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulations of the present invention have improved dissolution and permeability in fasted and fed state simulation that is expected to deliver full absorption and the elimination of the food effect.
