Young L. KIM,Raymond L. KONGER,Ally-Khan SOMANI,Zhengbin XU
申请号：
US13964722
公开号：
US20140046196A1
申请日:
2013.08.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
An apparatus and method of mesoscopic imaging which provide improved contrast to changes in tumor microenvironments are disclosed. The apparatus includes a light which illuminates tissue in vivo, a spectrometer which varies at least one parameter of the light, and optics which transmit light backscattered from the tissue. The optics comprise any one of (i) a small aperture 4-focal length (4-f) lens system within an angular cone of 2°-5°, (ii) a telecentric lens, and (iii) an anti-scatter grid and a camera lens.
