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Compositions for generating an antigen specific immune response
专利权人:
Helmholtz-Zentrum fur Infektionsforschung GmbH
发明人:
Zender, Lars
申请号:
AU2010277561
公开号:
AU2010277561A1
申请日:
2010.07.30
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention provides for the purposeful utilisation of the induction of senescence in eukaryotic cells for induction of an antigen specific immune response. Such cells can be normal cells, pre-malignant and malignant cells as well as virally or bacterially infected cells, for the generation of an immune response, preferably a cellular or humoral immune response comprising T-cells and/or B-cells, whose immune response is directed specifically against antigens from those cells in which senescence was induced and then comprises an immune response against the senescent cells itself as well as to the non-senescent counterparts harbouring the same antigens.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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