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VACCINE COMPOSITION
专利权人:
TURNSTONE LIMITED PARTNERSHIP
发明人:
David F. Stojdl,John Cameron Bell,Brian Lichty,Jonathan Pol
申请号:
US16249616
公开号:
US20190240301A1
申请日:
2019.01.16
申请国别(地区):
US
年份:
2019
代理人:
摘要:
There is described a kit for use in inducing an immune response in a mammal, the kit includes: a first virus that expresses MAGEA3, Human Papilloma Virus E6/E7 fusion protein, human Six-Transmembrane Epithelial Antigen of the Prostate protein, or Cancer Testis Antigen 1, or a variant thereof as an antigenic protein and that is formulated to generate an immunity to the protein or variant thereof in the mammal. The kit also includes a Maraba MG1 virus encoding the same antigen, or a variant of the same antigen. The Maraba MG1 virus is formulated to induce the immune response in the mammal. The first virus is immunologically distinct from the Maraba MG1 virus.
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