Disclosed herein is a modular composition comprising 1) an oligonucleotide； 2) one or more tetraGalNAc ligands of Formula (I), which may be the same or different； optionally, 3) one or more linkers, which may be the same or different； 4) one or more peptides independently selected from Table 3, which may be the same or different； and optionally, 5) one or more targeting ligands, solubilizing agents, pharmacokinetics enhancing agents, lipids, and/or masking agents.
