METHOD FOR PREPARING ACYCLOVIR 2/3 HYDRATE

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专利权人:

ZHEJIANG CHARIOTEER PHARMACEUTICAL CO.; LTD.

发明人:

PU, TONG,FAN, YI,CHEN, TIAN,LEI, MING,WANG, NAIXING,YANG, ZHEN,YANG, JIANMING

申请号：

EP10755417

公开号：

EP2412373A4

申请日:

2010.03.17

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Preparation of acyclovir 2/3 hydrate comprises mixing acyclovir with water at weight ratio of 1:5∼50, dissolving at 50∼100°C, filtering, cooling filtrate at 0∼30°C to precipitate crystal, collecting the crystal by filtration, and drying the crystal at 0∼150°C for 0.5∼24 hours to obtain acyclovir 2/3 hydrate. The preparation process is simple and suitable for industrial production. The prepared product has good and stable crystal form.

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中国工程科技知识中心

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http://www.ckcest.cn/home/