Without having a moderate hardness, while a rapid disintegrating property in the oral cavity, and without damage during the course of distribution, suitable for practical use even after moisture absorption, and can also produce a delay in disintegration time, and require more specialized formulation techniques to provide an orally disintegrating tablet that can be produced easily in common facilities without. Drug-containing particles (1) an average particle diameter 150~300μm, (2) spherical mannitol crystal particles, (3) 25 ℃, the viscosity of the 10 wt% water suspension is partially pregelatinized starch is 5~45mPa · s, and orally disintegrating tablets containing (4) starch powder.口腔内において速やかな崩壊性を有しながら、流通過程で損傷せず、吸湿後も実用に耐え得る適度な硬度を有し、しかも崩壊時間の遅延を生じることなく、さらに特殊な製剤技術を必要とせず一般的な設備で容易に製造可能な口腔内崩壊錠を提供する。(1)平均粒径150~300μmの薬物含有粒子、(2)球形マンニトール結晶粒子、(3)25℃、10質量%水懸濁液の粘度が5~45mPa・sである部分アルファ化デンプン、及び(4)デンプン粉末を含有する口腔内崩壊錠剤。
