INHIBITEURS DE BMI-1 PYRIMIDINES INVERSÉS SUBSTITUÉS

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专利权人:

PTC THERAPEUTICS; INC.

发明人:

LEE, CHANG-SUN,BAIAZITOV, RAMIL,CAO, LIANGXIAN,DAVIS, THOMAS, W.,DU, WU,LIU, RONGGANG,MOON, YOUNG-CHOON,PAGET, STEVEN, D.,REN, HONGYU,SYDORENKO, NADIYA,WILDE, RICHARD, GERALD

申请号：

EP13857326

公开号：

EP2922828A4

申请日:

2013.11.21

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Amine substituted reverse pyrimidine compounds and forms thereof that inhibit the function and reduce the level of B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the level of Bmi-1 to treat a cancer mediated by Bmi-1 are described herein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/