LEE, CHANG-SUN,BAIAZITOV, RAMIL,CAO, LIANGXIAN,DAVIS, THOMAS W.,DU, WU,LIU, RONGGANG,MOON, YOUNG-CHOON,PAGET, STEVEN D.,REN, HONGYU,SYDORENKO, NADIYA,WILDE, RICHARD GERALD
申请号：
CA2892045
公开号：
CA2892045A1
申请日:
2013.11.21
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Amine substituted reverse pyrimidine compounds and forms thereof that inhibit the function and reduce the level of B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the level of Bmi-1 to treat a cancer mediated by Bmi-1 are described herein.
