A process for producing micro-tablets or micro-pellets from pharmaceutical composition constituted of one or more salts of fumaric acid monoalky esters of the general formula and dialkyl fumarate of the formula wherein A is a bivalent cation from the series consisting of Ca, Mg, Zn or Fe or a monovalent cation from the series Li, Na or K, respectively, and n denotes the numeral 1 or 2 depending on the type of cation, said process comprising : mixing said one or more salts of fumaric acid monoalkyl esters and said dialkyl fumarate, optionally, in combination with commonly used pharmaceutical excipients and vehicles, and preparing micro-tablets or micro-pellets from the resultant mixture/product in the manner such as herein described/exemplified, said micro-tablets/micro-pellets being, on administration, capable for treatment of psoriatic arthritis, neurodermatitis, psoriasis and enteritis regionalis Crohn, without any severe side effects, as experienced from the same composition in hithertoknown tablet forms, but maintaining same, if not better, efficacy.
