ANTIDOTE THERAPEUTICS, INC.;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人:
Matthew W. KALNIK,Thomas THISTED,Everett STONE,Charles C. REED,Max RODNICK-SMITH
申请号:
US16483380
公开号:
US20200224176A1
申请日:
2018.02.02
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Described are nicotine-degrading enzyme variants that exhibit increased nicotine-degrading activity and/or decreased immunogenicity relative to the wild-type NicA2 and NOX enzymes, compositions comprising the variants, and methods using them.