Board of Regents, The University of Texas System;Antidote Therapeutics, Inc.
发明人:
Kalnik, Matthew W.,Thisted, Thomas,Stone, Everett,Reed, Charles C.,Rodnick-Smith, Max
申请号：
AU2018215456
公开号：
AU2018215456A1
申请日:
2018.02.02
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
Described are nicotine-degrading enzyme variants that exhibit increased nicotine-degrading activity and/or decreased immunogenicity relative to the wild-type NicA2 and NOX enzymes, compositions comprising the variants, and methods using them.
