ANDERSEN, KIM VILBOUR,ROEPKE, MADS,HAANING, JESPER MORTENSEN,GLAZER, STEVEN
申请号:
CA2519873
公开号:
CA2519873C
申请日:
2004.03.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Variants of FVII or FVIIa comprising at least one amino acid modification inposition 196, 237 or 341 relative to hFVII or hFVIIa. The variants exhibit anincreased clotting activity, i.e. reduced clotting time, compared to rhFVIIa.