Fundacion Centro National de Investigaciones Oncolgicas Carlos III
发明人:
Nabil Djouder,Krishna Seshu Tummala
申请号：
US15500199
公开号：
US20170312300A1
申请日:
2015.07.30
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention relates to nicotinamide riboside or a derivative thereof for use in the treatment and/or prevention of liver or pancreatic cancer in a subject. Additionally, the invention relates to an in vitro method for designing a customized therapy for a subject diagnosed with a liver cancer or pancreatic cancer or suffering early signs of chronic liver damage or pancreatic intraepithelial lesions based on determining the level of DNA damage. Additionally the invention also relates to a method for diagnosing liver cancer and for predicting the risk of developing liver cancer in a subject suffering hepatitis. The invention also relates to a kit and their use in the methods of the invention.
