JIANG, XIN,LIU, XIAOFENG,GREINER, JACK,SZUCS, STEPHEN, S
申请号：
NZ58871109
公开号：
NZ588711A
申请日:
2009.04.20
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
This disclosure relate to oleanolic acid derivatives represented by the structural formula depicted herein, wherein the variables are as defined in the specification. Also disclosed are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions. These compounds are suitable for the treatment and prevention of diseases such as those associated with oxidative stress and inflammation, and are particularly suitable for treating cancer selected from carcinoma, sarcoma, lymphoma, leukemia, melanoma, mesothelioma, multiple myeloma, or seminoma or for treating cancer selected from cancer of the bladder, blood, bone, brain, breast, central nervous system, colon, endometrium, esophagus, genitourinary tract, head, larynx, liver, lung, neck, ovary, pancreas, prostate, spleen, small intestine, large intestine, stomach, or testicle.
