PROBLEM TO BE SOLVED: To provide a new TNF-&alpha production inhibitor readily available as an ingredient derived from a plant, having high safety for the human body and capable of effectively inhibiting the production of the TNF-&alpha not only from macrophages but also from fat cells.SOLUTION: This TNF-&alpha production inhibitor comprises an active ingredient obtained from the plant of the genus Talinum of the family Portulacaceae.COPYRIGHT: (C)2003,JPO【課題】 植物由来成分として容易に入手できて、人体に対し安全性が高く、かつマクロファージからのTNF-αの産生のみならず、脂肪細胞からTNF-αの産生をも有効に抑制できる、新規なTNF-α産生抑制剤を提供すること。【解決手段】 スベリヒユ科ハゼラン属植物から得られる有効成分を含有するTNF-α産生抑制剤。
