<；P>；PROBLEM TO BE SOLVED: To prevent decrease of endogenous DHEA-S with age, or to increase the same by positively increasing the endogenous DHEA-S in the body of a subject. <；P>；SOLUTION: The pharmaceutical agent for increasing endogenous DHEA-S includes as a main ingredient self-original lymphocytes which are proliferator-activated by culturing lymph corpuscles collected from a subject in a culture solution containing a solid-phased anti-CD3 antibody and interleukin 2. The pharmaceutical agent positively increases a concentration of endogenous DHEA, particularly, DHEA-S in blood to provide an apparent antiaging effect. <；P>；COPYRIGHT: (C)2010,JPO&INPIT
