КИМ Сунгхоон (KR),ЧОИ Дзин Воо (KR),ЛИ Дзин Йоунг (KR),КИМ Дае Гиу (KR),ХАН Гиоон Хее (KR),ЯНГ Дзее Сун (KR),ЛИ Чул Хо (KR)
申请号：
RU2012123009/15
公开号：
RU2012123009A
申请日:
2010.11.05
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A pharmaceutical composition for prevention and treatment of cancer comprising as active ingredient a benzoheterocyclic derivatives represented by Formula 1 or a pharmaceutically acceptable salt [Formula 1] GDEPREDSTAVLYAET a double bond or a single bond (in which according to the requirements ATOMS is valid), A is selected from group consisting of O, NH and S X REPRESENTS C or N RVYBIRAYUT from the group consisting of hydrogen, alkyl, unsubstituted or substituted by halogen, alkoxy, halogen, nitro and amino RVYBIRAYUT FROM Group consisting of hydrogen, arylalkyl, and -NH-R R is hydrogen or alkyl, unsubstituted or substituted by halogen is aryl, unsubstituted or substituted with halogen, or aryl which is unsubstituted or substituted by halogen IRVYBIRAYUT from the group consisting of hydrogen, .2. PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF CANCER according to claim 1, wherein the active ingredient is selected from the group consisting of N- (6-methoxy-benzooxazol-2-yl) -benzamide FORMULA 2, N- (5-methoxy-benzooxazol-2-yl) -benzamide FORMULA 3, (5-chloro-benzooxazole-2-yl) phenylamino FORMULAS 4, (5-chloro-benzooxazole-2-YL) - (4-ethylphenyl) amine of formula 5, (5-chloro-benzooxazole-2-YL) - (3,4-dichlorophenyl ) Amine 6 (5-NITROBENZOOKSAZOL-2-YL) - (4-FENILAZOFENIL) an amine of formula 7, N-Benzooxazol-2-yl-benzamide FORMULA 8, N- (5-NITROBENZOOKSAZOL-2-yl) -benzamide FORMULA 9, N - (5-methoxy-benzooxazol -2-yl) -benzamide FORMULA 10, N- (5-METILBENZOOKSAZOL-2-yl) -benzamide FORMULA 11, N- (6-nitrobenzothiazole 2-YL) -4-trifluoromethyl-benzamide FORMULA 12 [2- (5-METILBENZOOKSAZOL- 2-yl) phenoxy] acetic acid of formula 13, 2- (2,4,6-trimethylphenyl) -benzooxazol-5-ylamine of formula 14, 2- [2- (4-methylbenzyl
