Enterococcus faeciumLJS-01 was isolated from swine intestine that has good antimicrobial activity. The strain inherent acid tolerance, bile salt tolerance, and strong capacity of adhesion on intestinal epithelial cells. The strain exhibited high capacity of colonization when testedin vitroandin vivo. Furthermore,E. faeciumLJS-01 has highly cholesterol degrading capacity, and contains enterocin A and enterocin B in the genome. Therefore, this microorganism has potential to replace antibiotics as feed additives, to be used as diarrea treatment agent for animal, and to develop as a health food.本發明關於一種分離自豬腸道的乳酸菌,該乳酸菌屬於糞腸球菌(Enterococcus faeciumLJS-01),經體外及體內試驗均證實有良好抗菌能力並具備耐酸、耐膽鹽及腸道上皮細胞強吸附能力以使其經口服後能順利進入腸道中拓殖。此外,本菌也具備膽固醇強降解能力及同時擁有腸菌素A及腸菌素B二種抗菌蛋白基因等多重益生性能之乳酸菌株。故本發明之乳酸菌具有開發替代抗生素作為飼料添加劑、動物下痢改善劑與健康食品之潛力。
