PROCEDES D'ISOLEMENT DE CELLULES T ET DE RECEPTEURS DES CELLULES T AYANT UNE SPECIFICITE ANTIGENIQUE POUR UNE MUTATION SPECIFIQUE AU CANCER DU SANG PERIPHERIQUE
THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
GROS, ALENA,ROSENBERG, STEVEN A.
申请号：
CA2984234
公开号：
CA2984234A1
申请日:
2016.04.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Disclosed are methods of isolating T cells and TCRs having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer.
