LEXIGEN PHARMACEUTICALS CORPORATION;THE SCRIPPS RESEARCH INSTITUTE
发明人:
LODE, HOLGER N.,REISFELD, RALPH A.,CHERESH, DAVID A.,GILLIES, STEPHEN D.
申请号:
CA2360106
公开号:
CA2360106C
申请日:
2000.02.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention teaches methods for treating tumors and tumor metastases in amammal comprising administering, to a mammal in need of treatment, atherapeutic amount of an antagonist sufficient to inhibit angiogenesis incombination with a therapeutic amount of anti-tumor immunotherapeutic agent,such as an anti-tumor antigen antibody/cytokine fusion protein having acytokine and a recombinant immunoglobulin polypeptide chain sufficient toelicit a cytokine-specific biological response.