THE SCRIPPS RESEARCH INSTITUTE, LA JOLLA;LEXIGEN PHARMACEUTICALS CORPORATION, LEXINGTON
发明人:
LODE, HOLGER N.,REISFELD, RALPH A.,CHERESH, DAVID A.,GILLIES, STEPHEN D.
申请号:
HU0200128
公开号:
HU229520B1
申请日:
2000.02.11
申请国别(地区):
HU
年份:
2014
代理人:
摘要:
The invention provides methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to inhibit angiogenesis in combination with a therapeutic amount of anti-tumor immunotherapeutic agent, such as a anti-tumor antigen antibody/cytokine fusion protein having a cytokine and a recombinant immunoglobulin polypeptide chain sufficient to elicit a cytokine-specific biological response.