Method for identifying agents capable of inhibiting APOBEC3C activity in HIV-infected cells

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专利权人:

Robert M. Grant

发明人:

Robert M. Grant,Khaoula Bourara

申请号：

US11577077

公开号：

US08133666B2

申请日:

2005.10.31

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention provides methods of identifying agents that reduce a level of active APOBEC3C in a cell. The present invention provides agents that reduce a level of active APOBEC3C in a cell and compositions comprising the agents. The present invention further provides methods of reducing the mutation rate of a lentivirus in a cell and methods of reducing the emergence of drug-resistant strains of lentivirus. The present invention further provides methods for treating lentivirus infections.

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中国工程科技知识中心

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http://www.ckcest.cn/home/