methods for increasing fetal hemoglobin levels in a cell and in mammal in need thereof, and for identifying a bcl11a expression or activity modulator

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专利权人:

President And Fellows Of Harvard College;Childrens Medical Center Corporation;Children's Medical Center Corporation

发明人:

Stuart H. Orkin,Viajay G. Sankaran

申请号：

BRPI0919017

公开号：

BRPI0919017A2

申请日:

2009.09.14

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The invention relates to methods and uses of modulating fetal hemoglobin expression (HbF) in a hematopoietic progenitor cells via inhibitors of BCL11A expression or activity, such as RNAi and antibodies.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/