CHEM-MASTER INTERNATIONAL, INC.;THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
发明人:
GOLUB, LORNE, M.,LEE, HSIMING,JOHNSON, FRANCIS
申请号:
EP12841310
公开号:
EP2768797A4
申请日:
2012.10.16
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
This invention provides a compound having the structure wherein α, &bgr;, A, B, and R1-R4 are defined herein. This invention also provides pharmaceutical compositions comprising the above compounds, a method of accelerating the healing of a wound, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NF&kgr;-B activation in a population of cells.