THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK;Chem-Master International, Inc.
发明人:
Francis JOHNSON,Lorne GOLUB
申请号：
HK18102646.4
公开号：
HK1243596A
申请日:
2018.02.23
申请国别(地区):
HK
年份:
2018
代理人:
摘要：
This invention provides a compound having the structure wherein &alpha；, &bgr；, X, Y, and R1-R11 are defined herein. This invention also provides a pharmaceutical composition comprising the above compounds, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NF&kgr；-B activation in a population of cells.
