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Curcumin analogues as zinc chelators and their uses
专利权人:
Lorne Golub;Francis Johnson
发明人:
Francis Johnson,Lorne Golub
申请号:
US14883074
公开号:
US09556105B2
申请日:
2015.10.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention provides a compound having the structurewherein α, β, X, Y, and R1-R11 are defined herein. This invention also provides a pharmaceutical composition comprising the above compounds, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NFκ-B activation in a population of cells.
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中国工程科技知识中心
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