Curcumin analogues as zinc chelators and their uses

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专利权人:

Lorne Golub;Francis Johnson

发明人:

Francis Johnson,Lorne Golub

申请号：

US14883074

公开号：

US09556105B2

申请日:

2015.10.14

申请国别(地区):

US

年份:

2017

代理人:

摘要：

This invention provides a compound having the structurewherein α, β, X, Y, and R1-R11 are defined herein. This invention also provides a pharmaceutical composition comprising the above compounds, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NFκ-B activation in a population of cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/