PURPOSE: A composition containing Rubus coreanus miquel extract is provided to prevent or treat hair loss by suppressing 15-PGDH activation without skin irritation. CONSTITUTION: A composition for hair growth contains Rubus coreanus miquel extract as an active ingredient. A method for preparing the Rubus coreanus miquel comprises: a step of juicing Rubus coreanus miquel and adding ethyl acetate to obtain aqueous layer and EtOAc-soluble acidic and neutral fraction； and a step of adding buffer to EtOAc-soluble acidic and neutral fraction.본 발명은 복분자 추출물을 함유하는 조성물에 관한 것으로, 본 발명의 조성물은 복분자로부터 분리한 천연원료로 피부에 대한 자극을 주지 않으면서, 15-하이드록시프로스타글란딘 디하이드로게나아제(15-hydroxyprostaglandin dehydrogenase, 15-PGDH)의 활성을 억제하여 탈모를 예방 또는 치료하는 효과를 제공한다.
