PURPOSE: A hangover relieving composition containing a glehnia littoralis extract as an active ingredient is provided to offer an activation promoting effect of the composition on ADH and ALDH to users.CONSTITUTION: A hangover relieving composition containing a glehnia littoralis extract as an active ingredient comprises the following steps: hot water-extracting glehnia littoralis at 90-100 deg C using water, C1-4 alcohol, or a C1-4 alcohol water solution for 1-6 hours filtering the obtained extract, and decompress-concentrating the filtrate and drying the obtained concentrate. The hangover relieving composition uses 100 parts of glehnia littoralis by weight mixed with 1-30 parts of medical herb by weight selected from hovenia dulcis, xanthium strumarium, paeonia lactiflora, or glycyrrhizae radix.COPYRIGHT KIPO 2012본 발명은 숙취해소용 조성물로, 해방풍으로 제조된 숙취해소용 조성물이며 알코올 분해효소인 ADH의 활성을 촉진시키는 효능이 있어 알코올섭취시 나타나는 숙취현상인 손떨림, 가슴 두근거림, 두통, 갈증, 멀미, 위장애, 설사 등을 개선하며, ADH와 ALDH의 활성을 촉진시키는 효과가 우수하여 에탄올을 최종 대사산물인 아세트산으로 빠르게 분해시키므로 알코올 섭취로 인한 각종 질환들을 예방 및 개선할 수 있다.