The Trustees of Columbia University in the City of New York
发明人:
Mao Jeremy J.,Chen Mo
申请号：
US201113877262
公开号：
US9597359(B2)
申请日:
2011.10.03
申请国别(地区):
美国
年份:
2017
代理人:
Dentons US LLP
摘要：
Described is a method of forming a mineralized material by co-culturing epithelial cell, such as ameloblast, and mesenchymal cell, such as osteoblast or odontoblast, in a mineral-stimulating medium. Also described is a matrix seeded with epithelial cells and mesenchymal cells and infused with a mineral-stimulating medium capable of forming a mineralized material in the matrix. Methods of manufacturing such compositions and methods of treating mineralization-related conditions are also described.
