The present invention provides: a hot flash suppressant comprising apelin or an apelin receptor agonist, wherein the apelin receptor agonist is selected from the group consisting of Rubus buergeri, Aster yomena, Stauntonia hexaphylla, Rubus grayana, Kalimeris indica, Lithocarpus edulis, Myrica rubra, Syzgium jambos, Quercus serrata and extracts of these plants, as well as a saffron extract, a pine extract, a cinchona extract, a comfrey extract, a Scutellaria extract, a rosemary extract, an apricot seed powder, a gentian extract, a thyme extract, a mint powder, a jujuba fruit extract, a hop extract, a kiwifruit extract, a roman chamomile extract, an apple extract, a hawthorn extract and a turmeric extract; and a screening method for a medical agent for improving hot flash.