The present invention provides: a hot flash suppressant which contains apelin or an apelin receptor agonist； the hot flash suppressant wherein the apelin receptor agonist is selected from the group consisting of Rubus buergeri, Kalimeris yomena, Stauntonia hexaphylla, Rubus grayanus, Kalimeris indica, Pasania edulis, Merica rubra, Syzygium jambos, Quercus serrata and extracts of these plants, as well as a saffron extract, a pine extract, a cinchona extract, a comfrey extract, a Scutellaria extract, a rosemary extract, an apricot seed powder, a gentian extract, a thyme extract, a mint powder, a Zizyphi fructus extract, a hop extract, a kiwifruit extract, a roman chamomile extract, an apple extract, a hawthorn extract and a turmeric extract； and a screening method for a medical agent for improving hot flash.
