4,6-DIAMINO-PYRIMIDINE DERIVATIVES AS BMI-1 INHIBITORS TO TREAT CANCER

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专利权人:

PTC Therapeutics; Inc.

发明人:

LEE, Chang-Sun,BAIAZITOV, Ramil,CAO, Liangxian,DAVIS, Thomas, W.,DU, Wu,LIU, Ronggang,MOON, Young-Choon,PAGET, Steven, D.,Ren, Hongyu,SYDORENKO, Nadiya,WILDE, Richard, Gerald

申请号：

DK13857326

公开号：

DK2922828T3

申请日:

2013.11.21

申请国别(地区):

DK

年份:

2020

代理人:

摘要：

Amine substituted reverse pyrimidine compounds and forms thereof that inhibit the function and reduce the level of B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the level of Bmi-1 to treat a cancer mediated by Bmi-1 are described herein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/