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NON-SELF T-CELL EPITOPE FUSED TO AN ANTIBODY THAT RECOGNISES A TUMOUR-SPECIFIC CELL-SURFACE RECEPTOR AND USES THEREOF
专利权人:
Antonello Pessi
发明人:
Antonello Pessi
申请号:
US14110122
公开号:
US20140161826A1
申请日:
2012.04.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A first composition comprising a ligand part being able to specifically bind to a target, the target being on a diseased cell of an organism, and an epitope part having a non-self epitope, or encoding a non-self epitope, the non-self epitope not naturally being encoded by the organism, wherein the target is internalized after forming a complex with the composition and the non-self epitope is presented on the cell surface of said diseased cell of an organism after internalization.
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