18F -GLUTATHIONE CONJUGATE AS A PET TRACER FOR IMAGING TUMORS OR NEUROLOGICAL DISORDERS THAT OVEREXPRESS L-PGDS ENZYME

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专利权人:

National Tsing Hua University

发明人:

Kun-Ju LIN,Chun-Nan YEH,Ying-Cheng HUANG,Ho-Lien HUANG,Chung-Shan YU

申请号：

US14957081

公开号：

US20160228584A1

申请日:

2015.12.02

申请国别(地区):

US

年份:

2016

代理人:

摘要：

A PET tracer for imaging tumors or neurological disorders that overexpress L-PGDS enzyme is provided. The present invention have prepared a glutathione conjugate of fluorine-18-labeled fluorobutyl ethacrynic amide using an acceptable amount of radioactivity that is capable of binding to L-PGDS and can be used for in vitro and in vivo imaging studies.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/