NOVEL ANTIBODIES INHIBITING C-MET DIMERIZATION, AND USES THEREOF

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专利权人:

PIERRE FABRE MEDICAMENT

发明人:

GOETSCH, LILIANE

申请号：

NZ59995908

公开号：

NZ599959A

申请日:

2008.07.10

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

Patent No. 599959 Disclosed is an isolated antibody, or one of its functional divalent fragments capable of binding to the c-Met, wherein the antibody or functional divalent fragment comprises a heavy chain comprising CDR-H1, CDR-H2 and CDR-H3 comprising respectively the amino acid sequences: GYSFTDYT, INPYNGGT, AREEITKDFDF and a light chain comprising CDR-L1, CDR-L2 and CDRL3 comprising respectively the amino acid sequences ESIDTYGNSF, RAS, QQSNEDPFT.

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