Disclosed is an isolated antibody, or one of its functional divalent fragments capable of binding to the c-Met, wherein said isolated antibody or said functional 5 divalent fragments comprises a heavy chain comprising CDR-H1, CDR-H2 and CDR-H3 comprising respectively the amino acid sequence SEQ ID Nos. 56, 57 and 58; and a light chain comprising CDR-L1, CDR-L2 and CDR-L3 comprising respectively the amino acid sequence SEQ ID Nos. 59, 60 and 61.