Novel antibodies inhibiting c-met dimerization, and uses thereof

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专利权人:

PIERRE FABRE MEDICAMENT

发明人:

GOETSCH LILIANE

申请号：

NZ61371608

公开号：

NZ613716A

申请日:

2008.07.10

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Disclosed is an isolated antibody, or one of its functional divalent fragments capable of binding to the c-Met, wherein the antibody or functional divalent fragment comprises a heavy chain comprising CDR-H1, CDR-H2 and CDR-H3 comprising respectively the amino acid sequences GYTFTDYN, INPNNGGT, and ARGRYVGYYAMDY； and a light chain comprising CDR-L1, CDR-L2 and CDRL3 comprising respectively the amino acid sequence ENIYSN, AAT, and QHFWGPPYT.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/