Zhaohui Sunny ZHOU,George ODOHERTY,Shanshan LIU,Kevin Ryan MOULTON,Lincoln OMBELETS,Amissi SADIKI
申请号：
US15985494
公开号：
US20180369131A1
申请日:
2018.05.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method is provided for reversibly modifying a protein or peptide on its glutamine residue(s) by performing a reaction, such as a transglutaminase-catalyzed reaction, between the protein or peptide and an amine-containing reagent, whereby the reagent is linked through its amine function to a side chain of the glutamine residue. Subjecting the modified protein to an appropriate stimulus regenerates the protein or peptide in its original form.
