Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide

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专利权人:

Alkermes; Inc.

发明人:

Juan Alvarez,Jean Chamoun,Heather C. Losey

申请号：

US14841809

公开号：

US10023623B2

申请日:

2015.09.01

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides fusion proteins comprising a mucin-domain polypeptide covalently linked to an active protein that has improved properties (e.g. pharmacokinetic and/or physicochemical properties) compared to the same active protein not linked to mucin-domain polypeptide, as well as methods for making and using the fusion proteins of the invention.

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