Eduardo J. Martinez,Andreas G. Grill,Aniruddh Singh,Padmini Kavuru,Nicholas D. Paschalides,Stephen A. Wald
申请号：
US15449428
公开号：
US09884813B1
申请日:
2017.03.03
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to new pharmaceutical salts of β-GPA which exhibit improved physical properties. In particular, the invention relates to salts of β-GPA with improved flow properties (e.g., improved Carrs index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of β-GPA, as well as methods of treating cancer including administration of a formulation including a β-GPA salt of the invention to a subject in need thereof.
