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Pharmaceutically acceptable salts of beta-guanidinopropionic acid with improved properties and uses thereof
专利权人:
Inc.;Rgenix
发明人:
Kavuru, Padmini,Martinez, Eduardo J.,Grill, Andreas G.,Singh, Aniruddh
申请号:
AU2016311368
公开号:
AU2016311368A1
申请日:
2016.08.25
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to new pharmaceutical salts of β-GPA which exhibit improved physical properties. In particular, the invention relates to salts of β-GPA with improved flow properties (e.g., improved Carr's index and/or Hausner ratio) such as fumarate salts, succinate salts, and oxalate salts. The invention also relates to pharmaceutical compositions including a pharmaceutically effective amount of one or more salts of β-GPA, as well as methods of treating cancer including administration of a formulation including a β-GPA salt of the invention to a subject in need thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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