ENHANCER FOR PROMOTER, AND USE THEREOF

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专利权人:

NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION

发明人:

MATSUURA, MASAAKI,TAKEMOTO, MASAYA,KOSHIZUKA, TETSUO,YAMANISHI, KOICHI,MORI, YASUKO

申请号：

EP10813526

公开号：

EP2474611A4

申请日:

2010.09.03

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Disclosed is an enhancer for a viral promoter such as a promoter that can induce expression selectively and strongly in immunocompetent cells (e.g., lymphocytes) or blood cells. It is found unexpectedly that an intron has the above-mentioned enhancer activity. Thus, it is found that an enhancer for a promoter, which comprises an intron sequence for a major immediate early gene (MIE) of human herpes virus-6 (HHV-6) (particularly HHV-6B) or a fragment of the intron sequence, has a potent promoter activity.

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