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ENHANCER FOR PROMOTER AND USE THEREOF
专利权人:
发明人:
MATSUURA MASAAKI,TAKEMOTO MASAYA,KOSHIZUKA TETSUO,YAMANISHI KOICHI,MORI YASUKO
申请号:
IN1985/CHENP/2012
公开号:
IN2012CN01985A
申请日:
2012.03.02
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
Disclosed is an enhancer for a viral promoter such as a promoter that can induce expression selectively and strongly in immunocompetent cells (e.g. lymphocytes) or blood cells. It is found unexpectedly that an intron has the above-mentioned enhancer activity. Thus it is found that an enhancer for a promoter which comprises an intron sequence for a major immediate early gene (MIE) of human herpes virus-6 (HHV-6) (particularly HHV-6B) or a fragment of the intron sequence has a potent promoter activity.
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