The present invention relates to novel modified macrocyclic compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).本發明係關於如本文所闡述及定義之通式(I)之新穎經修飾巨環化合物，及其製備方法，其用於治療及/或預防病症、具體而言係過度增殖病症及/或病毒引發之傳染病及/或心血管疾病之用途。本發明進一步係關於可用於製備該等通式(I)化合物之中間體化合物。
