There is provided herein formula (I) or the compounds and its pharmaceutically acceptable salt of (II), and include their compositions, with the various methods of what, including treating cancer, abnormal cell proliferation, angiogenesis, Alzheimer disease, tuberculosis, osteoarthritis, idiopathic pulmonary fibrosis and neurological condition/condition/disease.本文提供了式(I)或(II)的化合物及其藥學上可接受的鹽,以及包含它們的組合物,用於各種方法,包括治療癌症、異常細胞增殖、血管發生、阿爾茨海默病、肺病、骨關節炎、特發性肺纖維變性和神經學狀况/病症/疾病。