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ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE
专利权人:
发明人:
GALLOP MARK A.,GALLOP MARK A.,YAO FENMEI,YAO FENMEI,LUDWIKOW MARIA J.,LUDWIKOW MARIA J.,PHAN THU,PHAN THU,PENG GE,PENG GE
申请号:
PL04781926
公开号:
PL1660440T3
申请日:
2004.08.20
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs o f (.plusmn.) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof , methods of making prodrugs of (.plusmn .) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof, methods of usin g prodrugs of (.plusmn.) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof, and pharmaceutical compositions thereof for treating or preventing common diseases and/or disorders such as spasticity and/or acid reflux disease. The disclosures herein also relate to acyloxyalkyl carbamate prodru gs of (.plusmn.) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof which are suitable for oral administration and to sustained release oral dosage forms thereof.
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